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Customized NGS Panels

Flexible panel design and production based on two proprietary technology platforms.

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ProbeCap® NGS Probes

Hybrid capture with in-house design and manufacturing; supports SNV/Indel/CNV/SV from MRD at dozens of sites to the whole exome.

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CpGCap® Methylation Probes

Probes for methylation sequencing, enriching CpG sites for early detection and epigenetics research.

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RealCap® Multiplex PCR

Optimized primer algorithm and reaction chemistry cover dozens to hundreds of targets per tube — ideal for fusion and hotspot detection.

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Supporting Reagents

Core reagents that improve capture efficiency and specificity.

Universal BlockerUniversal Blocker
Essential

Universal Blocker

Blocks library adapters and indexes (ILMN/MGI Lib) in NGS hybrid capture, reducing non-specific enrichment.

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Universal BlockerHuman Cot-1 DNA
Featured

Human Cot-1 DNA

Repetitive DNA to enhance NGS capture, microarray and FISH experiments.

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Universal BlockerUMI  adptor/UDI index kit For MGI/ILMN Lib Prep
Library Prep Reagents

UMI adptor/UDI index kit For MGI/ILMN Lib Prep

Can be adapted for NGS library construction such as ILMN/MGI, and UMI adapter is used for cfDNA library construction.

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Ready-to-Use Panels

The series of products are standardized panels for detection scenarios such as solid tumors, genetic diseases, RNA fusion, HLA typing, mitochondrial full-length sequencing, and whole exome sequencing.

BCP2000
New · Recommended

BCP2000 Tumor Panel

Covers 1900+ solid tumor genes for targeted therapy, MSI, chemotherapy and TMB analysis.

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BCP2000
Fusion

Cancer RNA Fusion Panel

RNA-level fusion detection panel supporting fusion discovery and companion diagnostics research.

Details →View datasheet PDF ↗
BCP2000HLA-Small /HLA-BIG Panel
Probe

HLA-Small /HLA-BIG Panel

Through hybrid capture, sequencing data is analyzed to perform high-precision typing of human HLA-related genes.

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BCP2000Full-length mitochondrial chromosome (ChrMT)
probe

Full-length mitochondrial chromosome (ChrMT)

Targeted capture to obtain the full-length 16 kb region of mitochondrial DNA.

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Hybrid Capture Reagents Comparison

Specifications across hybrid capture reagent versions.

Compare10X Standard WashHS Minimal WashHS OneTube newHS OneTube-tNGS newLibCap Pre-filled hot
PlatformMGI/GeneMind/Illumina/IONMGI/GeneMind/Illumina/IONMGI/GeneMind/IlluminaMGI/GeneMind/IlluminaMGI/GeneMind/Illumina
Wash Steps10X Standard Wash1X Minimal Wash1X Minimal Wash1X Minimal WashPre-filled
Library Prep TimeManuaManuaManuaManuaFor Homgen LibCap workstation
ProductStandard libraryStandard libraryStandard librarytNGS library标准文库
HighlightsClassic workflow, broad compatibilitySimplified wash, higher efficiencySingle-reagent operation to reduce errors.Targeted tNGS specificAutomation workstation fit
Release time20192023202520262024
Hybridization time4~16h1~16h1~16h0.25-2h1~16h

Human Whole-Exome Panel Comparison

Specifications across whole-exome panel versions.

CompareHomExon V3 newHomExon V3 For Cancer hotHomExon V3 add10KSNPHomExon C17HomExon Y15Hi-Exon 35 / 35V2
Targets~20,000 genes~20,000 genes~20,000 genes~6,000 genes~5,000 genes~19,500 genes
Capture efficiency> 80%> 80%> 80%> 80%> 80%> 80%
0.2X Mean> 99%> 99%> 99%> 99%> 99%> 99%
Region size~40M~41M~42M~17M~15M~39M
Number of coding regions~210,000~210,000~210,000~80,000~70,000~200,000
Tumor intronNAALK/ROS1/MET/NTRK...NAALK/ROS1/MET/NTRK...NAALK/ROS1/MET/NTRK...
Full length of mitochondria√√√NA√√
HLA√√√√√√
Chemotherapy/MSI sites√√√√NA√
Genome-wide SNP backboneNANA√NA√NA
ClinVar L/P sites √√√√√√
Individual personalized areaavailableavailableavailableavailableavailableavailable
HBA/TERT-p/snRNA√√√√√NA
ApplicationRare disease / genetics / Large-scale screeningClinical diagnostics For CancerClinical diagnostics For geneticsTumor Initial Screening: MRD Target Selectiongenetic disorder screeningWhole-exome sequencing research and testing
Reference databaseRefSeq/GENECODE/HGMDRefSeq/GENECODE...RefSeq/GENECODE/HGMDRefSeq/GENECODE/HGMDRefSeq/GENECODE/HGMDRefSeq
Sequencing data : 100X7.5G8G8G3G3G9G
Special RegionWhole Exon Version V3The sequencing depth in tumor gene regions is deeper.Genome-wide SNP backboneSelect core tumor genes and their upstream and downstream genes.Select 5,000 genes directly related to genetic disorders.Whole Exon Version V1 /V2

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